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Hemangoendothelioma. Presented by Dr. Sigmund S. Greenbaum and Dr. Louis Goldstein.
J. M., a white man aged 59, of fair general appearance but obese and with teeth in poor condition, presents a pea-sized indurated area infiltrating deeply into the tissue of the right aspect of the lower lip. The center shows a punched-out ulceration with scaliness. Metastasis has not been noted. Serologic reactions of the blood for syphilis were negative.
The report on the biopsy was as follows: "The epidermis exhibits an acanthosis which amounts almost to a pseudoepitheliomatous hyperplasia. The superficial parts of the corium contain numerous telangiectases and a heavy infiltration of lymphocytes. The commanding lesion is an infiltrating malignant tumor which is located deep in the corium and extends into the underlying skeletal muscle bundles. Although the tumor is well outlined, it is not encapsulated. Additional strands of malignant cells infiltrate the surrounding
Wright CS, Thomas CC. PHILADELPHIA DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1944;49(4):287–292. doi:10.1001/archderm.1944.01510100063019
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