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Article
May 1944

MYCOSIS FUNGOIDES WITH BULLOUS LESIONS: SPECIAL TESTS AND LABORATORY DATA INDICATING ADRENAL INSUFFICIENCY

Author Affiliations

NEW YORK

From the Skin and Cancer Unit of the New York Post-Graduate Medical School and Hospital, Columbia University, New York, clinic of Dr. Fred Wise.

Arch Derm Syphilol. 1944;49(5):315-320. doi:10.1001/archderm.1944.01510110013004
Abstract

In a previous publication,1 a case of mycosis fungoides in which the conventional infiltrative and ulcerative lesions were accompanied by bullous elements was reported. The paper dealt mainly with the clinical, pathologic and therapeutic aspects of the case. The present contribution is devoted to the interpretation of special examinations and laboratory investigations which were performed mainly for the purpose of demonstrating the existence of pathologic alterations in the adrenal glands and the relationship of the alterations to the clinical phenomena.

REPORT OF A CASE

D. K., aged 65, had a bullous eruption arising from lesions of mycosis fungoides. These bullae ruptured spontaneously and left raw, denuded, hemorrhagic areas. The bullae were resistant to various types of routine and of special dermatologic therapy, but they responded rapidly to androgenic medication. A noteworthy coincidence was the disappearance, or "shedding," of almost all the coincidental seborrheic verrucae

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