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It has long been known that malaria, lymphogranuloma venereum, leprosy, vaccinia and other nonsyphilitic diseases may produce false positive serologic reactions. The following report of a case presents evidence that lupus erythematosus can be added to this list. Furthermore, it is believed that this patient had symptoms of lupus erythematosus before the appearance of cutaneous lesions.
REPORT OF A CASE
A 23 year old man enlisted in the Navy on June 27, 1941, in good health and with a normal skin and a negative Kahn reaction. On November 21 he reported to the sick bay complaining of painful feet. The Kahn reaction on his admission was reported as 3 plus. Twenty-three days later, on December 14, since all pain had subsided and the Kahn reaction had reverted to negative, although no antisyphilitic treatment had been instituted, the positive reaction was considered falsely positive and he was discharged
Sompayrac L, Hailey HE. LUPUS ERYTHEMATOSUS WITH FALSE POSITIVE KAHN REACTIONS. Arch Derm Syphilol. 1944;49(5):355. doi:10.1001/archderm.1944.01510110053013
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