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August 1944


Author Affiliations

President; Secretary Oct. 26, 1943

Arch Derm Syphilol. 1944;50(2):138-145. doi:10.1001/archderm.1944.01510140061017

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Pachyonychia Congenita. Presented by Dr. George C. Andrews.

Y. S., a man aged 25, of Turkish origin, was recently referred to me by Dr. Udo Wile. The patient has had a disfigurement of the finger nails and toe nails since birth. The nails loosen and fall off if injured in any way. There is no history of any eruption on other parts of the body. No members of his family have a similar condition.

Examination showed great thickening of all finger nails and toe nails, which increased toward the free borders. There was no leukokeratosis of the tongue or follicular keratosis on the glabrous skin, and no bullae were seen on the feet. The teeth were normal. Scrapings from the nails showed no fungi. The serologic reaction of the blood for syphilis was negative. At Dr. Wile's clinic, the basal metabolic rate had been determined, and the patient had

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