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September 1944


Author Affiliations

Dallas, Texas.

Arch Derm Syphilol. 1944;50(3):202. doi:10.1001/archderm.1944.01510150054014

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To the Editor:—I have had occasion recently to use penicillin locally for 4 patients, with such dramatically good results that I hope you will publish this letter in the Archives. All of these patients had "incurable dermatoses.''

Three patients, all men between 40 and 60 years of age, had what are usually called neurotic excoriations. The duration of the disease varied from two to twenty years in these 3 men. The number of excoriated crusted lesions, constantly present, varied from three to twenty. The favorite site was the nape of the neck and the scalp, with occasional lesions on the face. All 3 men had consulted several excellent dermatologists and had had adequate orthodox dermatologic therapy, with invariably poor results.

With local application of penicillin the lesions healed in from three to ten days. Within twenty-four hours there was relief from the paroxysmal itching. The penicillin solution which was

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