It has been shown by Lawrow and Dubowskoj (1937),1 by Berberian (1939),2 by Senekji and Beattie (1941)3 and by Katzenellenbogen (1942)4 that it is possible to produce oriental sore on any part of the body by injecting a suspension of living culture of Leishmania tropica into the skin. It has also been shown that a naturally acquired or an artificially induced sore will on healing produce sufficient immunity to protect the individual against reinfection. This procedure, however, will necessitate the maintenance of fresh cultures of L. tropica by physicians who may wish to use it as vaccine. As it is difficult to maintain cultures of L. tropica for physicians practicing in outlying districts where oriental sore is endemic or hyperendemic, it becomes necessary to prepare suspensions of live L. tropica in a central laboratory and issue it to those at
BERBERIAN DA. CUTANEOUS LEISHMANIASIS (ORIENTAL SORE): III. PERIOD OF INFECTIVITY OF SALINE SUSPENSIONS OF LEISHMANIA TROPICA CULTURES KEPT AT ROOM TEMPERATURE. Arch Derm Syphilol. 1944;50(4):233. doi:10.1001/archderm.1944.01510160005002
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