The many unusual complications of the following case of generalized scleroderma with acrodermatitis chronica atrophicans are of such rarity that it is deemed worthy of recording. This case further illustrates the many and varying manifestations of scleroderma, a disease the pathogenesis of which is obscure and the prognosis of which internists today regard as serious, especially in the generalized form.
REPORT OF A CASE
History.—Mrs. A. S., a white woman aged 46, was admitted to the New York Post-Graduate Medical School and Hospital on Jan. 5, 1944, complaining of a generalized eruption of three years' duration and pains in the joints of two years' duration.
Present Illness.—About three years ago a pruritic erythematous and edematous eruption developed on the dorsa of the patient's hands. One week later she became aware of a similar eruption involving the vulva and the perineal and perianal areas. She then
KANEE B. SCLEROPOIKILODERMA WITH CALCINOSIS CUTIS, RAYNAUD-LIKE SYNDROME AND ATROPHODERMA. Arch Derm Syphilol. 1944;50(4):254–260. doi:10.1001/archderm.1944.01510160026012
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