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Article
November 1944

SPECTROGRAPHIC ANALYSIS OF GOLD IN THE SKIN FOLLOWING TREATMENT OF LUPUS ERYTHEMATOSUS

Author Affiliations

PITTSBURGH

From the Department of Dermatology and the Department of Industrial Hygiene, University of Pittsburgh School of Medicine.

Arch Derm Syphilol. 1944;50(5):315-319. doi:10.1001/archderm.1944.01510170029007
Abstract

During the past eight years, we have been studying a group of patients whose response to gold therapy had not been satisfactory from a clinical standpoint. These patients had received various amounts of gold sodium thiosulfate both by the intravenous and by the intramuscular route. In 1931 Monash and Traub1 introduced a method of treatment for lupus erythematosus by means of intracutaneous injection of gold sodium thiosulfate and reported favorable response. The question then arose whether or not the presence of gold in lesions of lupus erythematosus under treatment with gold sodium thiosulfate had any effect in the healing of these lesions. In order to determine this point, it became desirable in this experiment to collect data with respect to the presence or absence of gold in normal skin, in active lesions and in healed lesions, as well as to study the relationship of the

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