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February 1945


Arch Derm Syphilol. 1945;51(2):81-89. doi:10.1001/archderm.1945.01510200005001

One of the newest of all scientific instruments, which in only three years has a remarkable record for achievement, is the electron microscope. With it has developed an entirely new branch of physics known as electron optics. The present and the potential applications of electron optics and this powerful new instrument to the medical field of dermatology and syphilology are the subject of this brief preliminary paper. Electron micrographs obtained largely with the RCA instrument at the University of Illinois are used to illustrate the new facts of structures at high magnifications of cutaneous tissues of several kinds, individual cells and single protein molecules.

The University of Toronto, under the leadership of Prof. E. F. Burton, pioneered the development of this new science on this continent with a homemade equipment. There were only two or three other homemade installations in the United States prior to the

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