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March 1945


Author Affiliations

Medical Director, Hersch-Razel Research Foundation; Medical Director, the Skin and Cancer Hospital of Philadelphia; Chief, Gastrointestinal Department, the Skin and Cancer Hospital of Philadelphia; PHILADELPHIA

From the Department of Dermatology, the Skin and Cancer Hospital of Philadelphia

Arch Derm Syphilol. 1945;51(3):189. doi:10.1001/archderm.1945.01510210031006

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While the clinical pictures of the various forms of infantile eczema are concise, the causative factors are far from clearcut. Infants with eczema are frequently given various diets based either on the results of cutaneous tests with atopic substances or on data obtained by food elimination. But these diets often fail to produce curative results. Occasionally one of us (A.S.) has witnessed a favorable result in infantile eczema following internal administration of large doses of dilute hydrochloric acid. So this investigation was undertaken in an effort to determine the status of the gastric secretion in infants with eczema.

The literature records a number of observations bearing on the question of secretion of gastric acid in infants and young children. These can be summarized in the statement that the free hydrochloric acid and the total acidity are considerably lower in healthy infants and young children than

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