Shortly after the report by Robinson and Wallace1 concerning the use of penicillium gauze in the treatment of cutaneous ulcers and infections, one of us (H. J. T.) began to use this method of treatment in his practice. The culture of penicillium notatum was furnished by David Singman, M.D., pathologist at the Cowel Memorial Hospital of the University of California, after he had checked it for its bactericidal activity in vitro.
We have used the penicillium gauze only for infected superficial ulcers, such as infected ulcers of the legs or ulcerative pyodermas or the deep type of pyoderma known as Bockhart's impetigo. There is no question in our minds that it is of great value in controlling infection in such cases, and it was used in 13. When it was apparent clinically that the lesions were solely orlargely due to local infection, the results were excellent,
TEMPLETON HJ, CLIFTON CE, SEEBERG VP. LOCAL APPLICATION OF PENICILLIN FOR PYOGENIC DERMATOSES. Arch Derm Syphilol. 1945;51(3):205–208. doi:10.1001/archderm.1945.01510210047012
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