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Article
April 1945

ULCERATIVE HODGKIN'S DISEASE AND LYMPH NODE IMPRINTS

Author Affiliations

MINNEAPOLIS

From the Division of Dermatology, University of Minnesota, and the Minneapolis General Hospital.

Arch Derm Syphilol. 1945;51(4):229-236. doi:10.1001/archderm.1945.01510220003001
Abstract

Cases of Hodgkin's disease with cutaneous manifestations have previously been studied with the usual fixation technic of the skin and node tissue. We wish to report the great value of node and skin imprints in the study of this disease. The frequency of cutaneous involvement has been given by different authors as varying from 16 per cent (by Barron1) and 29 per cent (by Wallhauser2) to 38 per cent (by Goldman3 and Cole4). Miller5 has mentioned that these manifestations are of two types, the nonspecific and the specific. The nonspecific manifestations, lacking the characteristic histopathologic changes, include diverse conditions ranging from generalized pruritus, lichenification, urticaria, prurigolike nodules, bullous eruptions, exfoliative erythrodermas and pigmentation to loss of hair and changes in the nails. They have also been labeled as "ids" or lymphogranulids by Nanta and Chatellier.6 The specific lesions, those hav

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