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July 1945


Arch Derm Syphilol. 1945;52(1):11-13. doi:10.1001/archderm.1945.01510250016004

Scent, whether organic or inorganic in origin, has a physicochemical basis and is propagated by minute particles. These odoriferous particles are termed osmyls and may act as inhalant allergens. The subject of allergy to scent or to osmyls has received but meager attention, if one is to judge from the few brief references in the literature. Among the authors who have advanced this etiologic conception are Feinberg and Aries,1 Rappaport and Hoffman,2 Urbach,3 Sulzberger and Wolf4 and Horesh.5

That perfumes as contactants frequently cause dermatitis is well known. Downing,6 Schwartz and Tulipan,7 and Rattner and Pusey,8 to mention but a few, have repeatedly called attention to the importance of scented cosmetics as a cause of dermatitis. The role of perfume, however, as an allergen causing chronic urticaria due to inhalation of osmyls has been seldom considered.

A report, therefore,