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August 1945


Arch Derm Syphilol. 1945;52(2):89-90. doi:10.1001/archderm.1945.01510260019003

Chronic discoid lupus erythematosus has been treated by many methods. It is not the purpose of this paper to review the literature or to describe any or all of these procedures but it is the purpose to submit a report on the results of therapy with biweekly injections of small doses of oxophenarsine hydrochloride (mapharsen).

During the past twenty months, 21 patients with chronic discoid lupus erythematosus have been studied and treated, and the results have been most encouraging. The use of small doses of oxophenarsine hydrochloride in the treatment of this disease was first suggested by Sulzberger1 and, on several occasions since, its use has been mentioned by Wise2 in the transactions of dermatologic societies in the Archives of Dermatology and Syphilology. Hyman3 stated that he used oxophenarsine hydrochloride with excellent results for 16 patients with chronic discoid lupus erythematosus, some of whom

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