To our knowledge, multiple infection of the nails with more than one species of fungus has never before been reported. The presence of a Trichophyton and an Aspergillus together is unusual in human tissue. Onychomycosis caused by the genus Aspergillus alone is extremely rare; in fact, the aspergilli have usually been considered, and often are, contaminants of mycologic cultures. There are only a few recorded instances of fungous infections of the nails attributed to the aspergilli and related fungi.
The first case reported was that of Émile-Weil and Gaudin,1 in 1919. Sartory2 reported a case in 1920 and Ota3 another in 1923. Sartory and co-workers4 reported another case in 1930. Smith5 reported a case in 1934. From 1934 until 1941 no other cases were published.
In 1941 Bereston and Keil6 reported the last case of aspergillosis of the nails to be
BERESTON ES, WARING WS. ONYCHOMYCOSIS AND DERMATOMYCOSIS CAUSED BY TRICHOPHYTON RUBRUM AND ASPERGILLUS NIDULANS. Arch Derm Syphilol. 1945;52(3):162–165. doi:10.1001/archderm.1945.01510270020003
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