Two cutaneous manifestations have been described in association with polycythemia: a purplish redness of the gums, due to a high concentration of hemoglobin, and a papular urticarial eruption with a surmounting vesicle or pustule occurring in crops, decidedly itchy and with bloody crusts. This eruption has unfortunately been termed acne urticata polycythaemica (Kaposi). Up to the present about 12 cases have been reported.
Klauder1 reported an instance of such an eruption in a patient who presumably suffered from polycythemia, although there was some doubt as to whether the disease might have been leukemia. The patient was a white woman, aged 58, who suffered from an itchy papular eruption which persisted and which occurred in crops. The primary lesion was an urticarial papule with a vesicle of pustule on top. The patient had hypertension, and the liver and spleen were enlarged. The blood had a high uric acid
STRICKLER A. POLYCYTHEMIA WITH AN UNUSUAL ERUPTION. Arch Derm Syphilol. 1945;52(3):172–173. doi:10.1001/archderm.1945.01510270030005
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