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October 1945


Author Affiliations

Chairman; Secretary May 6, 1944

Arch Derm Syphilol. 1945;52(4):275-283. doi:10.1001/archderm.1945.01510280059018

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A Case for Diagnosis (Fixed Bismuth Dermatitis?). Presented by Dr. Hal E. Freeman.

The patient is a Negro woman, aged 31. Two years ago she was found to have syphilis of the central nervous system. Until three months ago she had received nine injections of oxophenarsine hydrochloride, twenty-nine injections of tryparsamide and nineteen injections of a bismuth preparation. Beginning three months ago six more injections of bismuth subsalicylate, in doses of 1 cc., were given. The present eruption began two weeks after the first injection of the last series. The first lesion of the present eruption was an oval plaque, about 3 cm. long, on the left thigh. Soon another, similar, lesion appeared on the abdomen. In the last ten days numerous other lesions have developed.

The patient is a moderately well nourished Negro woman. On the anterior surface of the left thigh and on the lower

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