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Bowen's Disease of Penis; Late Latent Syphilis (Treated). Presented by Dr. James Strauch and Dr. S. Colimodio.
R. M., a Negro aged 51, was previously presented before the Cleveland Dermatological Society from the department of dermatology, University Hospitals, as "A Case for Diagnosis (Chronic Balanoposthitis?)."
The penile lesions have shown no real change in the past four years. The glans penis continues to exude and is painful.
A second biopsy was made on Jan. 9, 1941. Sections showed hyperkeratosis and patchy parakeratosis. There was definite acanthosis. Rete pegs were elongated. There was variation in the appearance of cells of the malpighian layer. There were many vacuolated cells with eccentrically placed nuclei and others decidedly swollen. Some cells had circular, deeply chromatic, irregularly shaped nuclei that were surrounded by small clear spaces. The nuclei were hyperchromatic. There were many atypical mitotic figures.
Numerous lymphocytes and large round cells infiltrated the
Driver JR, Binkley GW. CENTRAL STATES DERMATOLOGICAL SOCIETY: Meeting Held Under the Auspices of the Cleveland Dermatological Society. Arch Derm Syphilol. 1945;52(5):413–423. doi:10.1001/archderm.1945.01510290118028
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