MANY reports from English and American investigators indicate that local applications of penicillin are useful in the treatment of pyogenic infections of the skin. Bodenham1 found that a penicillin cream was effective in eliminating streptococci and staphylococci from burns and surface wounds. Roxburgh, Christie and Roxburgh2 prepared a penicillin ointment and a penicillin spray. They reported that local applications of penicillin were effective in the treatment of sycosis barbae and impetigo. Taylor and Hughes3 applied penicillin ointment and penicillin in a spray to lesions of impetigo, sycosis barbae and furunculosis, with favorable results. Sophian and Connolly4 treated acute and chronic pyogenic infections of the skin with a penicillin ointment containing a wetting agent. The results were good, especially in furunculosis and sycosis barbae. Schoch5 applied the washings of "empty" penicillin ampules to the lesions of 4 patients with diseases of the skin and was enthusiastic as to the
GOTTSCHALK HR, ENGMAN MF, MOORE M, WEISS RS. PENICILLIN OINTMENT IN THE TREATMENT OF SOME INFECTIONS OF THE SKIN. Arch Derm Syphilol. 1946;53(3):226–231. doi:10.1001/archderm.1946.01510320016002
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