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Article
March 1946

SPOROTRICHOSIS WITH RADIATE FORMATION IN TISSUE: Report of a Case

Author Affiliations

Mycologist to the Barnard Free Skin and Cancer Hospital; the Barnes Hospital; and the Department of Dermatology, Washington University School of Medicine; Pathologist to the Ellis Fischel State Cancer Hospital, Columbia, Mo.; Assistant Professor of Pathology, Washington University School of Medicine ST. LOUIS

Studies, observations and reports from the Laboratory for Mycology of the Department of Dermatology of the Barnard Free Skin and Cancer Hospital, service of Dr. M. F. Engman, Sr., and from the Ellis Fischel State Cancer Hospital.

Arch Derm Syphilol. 1946;53(3):253-264. doi:10.1001/archderm.1946.01510320043007
Abstract

RADIATE formation on cells of Sporotrichum was first observed by Splendore in 1908 and termed by him asteroid formation.1 These star-shaped bodies were found extracellularly in pus obtained from a verrucous, vegetative, hard and somewhat elastic lesion, present for twenty days, on the right side of the face of an Italian woman living in Sâo Paulo, Brazil.2 Pure cultures of the fungus were obtained from this lesion and from two lymph nodes, the size of kidney beans, just beneath the primary site. The lesion began as a small button, increased in size gradually to take on the verrucous appearance and was a little pruritic. The nodes developed secondarily. The lesion cleared in a few days with potassium iodide taken internally and topical application of mild mercurous chloride ointment. The cultures were identified as Sporotrichum and because of the radiate formation of the cells in tissue

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