This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
Pigmentation Following Morphea (and Arsenic?). Presented by Dr. Earle R. Pace.
Mrs. J. L., a white woman aged 22, presents a widespread pigmentary disturbance of the neck, trunk and proximal segments of the extremities. The onset coincided with the onset of menstruation ten years ago. The earliest patches were in the cubital fossae and on the upper part of the inner thighs and were hard, thickened and inflexible. New patches have appeared from time to time, all eventually resulting in pigmentation as now seen.
At present she shows coin-sized to egg-sized brown, pigmented patches, which fuse into sheets in many areas. The pigmentation is a smooth tan to brown discoloration, flecked with lighter spots. On the trunk, particularly on the abdominal wall, it is diffuse and nonmarginated and resembles arsenical pigmentation.
The central parts of some larger patches, notably in the cubital fossae and on the thighs, show
Wieder LM, Caro MR. CHICAGO DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1946;53(5):540–551. doi:10.1001/archderm.1946.01510340106017
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: