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June 1946


Author Affiliations


From the Division of Dermatology, University of Minnesota, H. E. Michelson, M. D., Director.

Arch Derm Syphilol. 1946;53(6):643. doi:10.1001/archderm.1946.01510350083015

In 1941 Sommerville1 reported on 8 cases of molluscum contagiosum in which the patients had been treated with sulfapyridine. In 6 cases the disease cleared completely, and in 2 it was necessary to stop the treatment within a short time because of toxic reactions to the drug. Sommerville pointed out that sulfapyridine had a definite lethal effect on the causative virus of molluscum contagiosum. Four of Sommerville's patients who took sulfapyridine regularly in doses of 30 to 60 grains (2 to 4 Gm.) daily were cured within varying periods of two to eight weeks. For 2 patients who took the drug only at irregular intervals three to four months was required for complete cure. Two patients who failed to respond when the daily dose was 15 grains (1 Gm.) had clearing when the dosage was increased to 30 grains daily. Of the 6 patients who were cured, 5 were

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