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June 1946


Arch Derm Syphilol. 1946;53(6):667-677. doi:10.1001/archderm.1946.01510350107021

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A Case for Diagnosis (Pigmentation of Lip and Buccal Mucosa). Presented by Dr. John C. Graham.

Mrs. I. R., 51 years, is a graduate nurse. About two years ago she first noticed a pigmented spot on the right side of the lower lip, inside the vermilion border. Similar spots have spread gradually to involve other parts of the mucosa of the lower lip and the buccal mucosa of both cheeks to some extent. There have been no subjective symptoms. Neither has there been any history of drugs applied locally or taken internally.

The pigmented areas are not indurated, and they appear normal in every way except for the deposit of pigment, which is increasing in extent. The individual patches are not getting darker. The principal complaint is the disfigurement.


Dr. A. Benson Cannon: For many years I have frequently observed patients with such brown pigmented spots on the mucous

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