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Article
July 1946

ERYSIPELOID: SUCCESSFUL TREATMENT WITH PENICILLIN: Report of a Case

Author Affiliations

MEDICAL CORPS, ARMY OF THE UNITED STATES

Arch Derm Syphilol. 1946;54(1):57-59. doi:10.1001/archderm.1946.01510360061007
Abstract

THE BEST treatment of erysipeloid is debatable. Klauder1 stated "that it is difficult to evaluate different methods of treatment, since in many cases erysipeloid apparently runs a self-limited course and splinting the hand may be the only required treatment." In an experimental study, Klauder and Rule2 reported a survival of 12.5 per cent of mice treated with a sulfonamide compound after inoculation with Erysipelothrix rhusiopathiae; this is surely a limited therapeutic effect of sulfanilamide, sulfapyridine, sulfathiazole and sulfadiazine. They also reported that sulfonamide compounds were ineffective in the treatment of patients with erysipeloid.

The opposite view has been expressed by other authors. Schoch and Shelmire3 and Eckstein4 reported success with sulfanilamide; Kulchar and Rosenberg5 cured erysipeloid with sulfathiazole. In the septicemic form with endocarditis, neither sulfanilamide6 nor sulfathiazole7 proved to be effective therapeutic agents.

The use of anti-erysipelothrix-rhusiopathiae serum was recommended

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