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The variety of gangrene here reported on is not of great interest in regard to causation. But my interest was aroused by its clinical form which I believe has never been recorded before, as I have found no case similar to mine in medical literature. The name, cutaneous iridiform gangrene, chosen by me was based on similarity between the iridiform lesions of the syphilis found in Negroes and the arrangement of my patient's lesion in concentric and excentric circles.
My patient's skin, which is black, took on a much more intensely black shade, which was almost generalized over the body, constituting a true melanoderma brought on by the absorption of mercury.
According to the patient's statement, the excentric progress of the gangrene took place as follows: Some days after the application of the mercury salt, preferably in the recent peripheral groove, a certain part of the skin outside that groove
COSTA OG. CUTANEOUS IRIDIFORM GANGRENE DUE TO A CHEMICAL AGENT. Arch Derm Syphilol. 1946;54(1):63–65. doi:10.1001/archderm.1946.01510360067010
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