Culp and Kaplan1 made a notable contribution to the treatment of condyloma acuminatum with resin of podophyllum. They used a 25 per cent suspension of resin of podophyllum in liquid petrolatum applied with a cotton swab to the surface of the lesions. They found that the growths became blanched in a few hours, appeared necrotic twenty-four to forty-eight hours later, began to slough on the second or third day and promptly disappeared.
I can testify to the efficacy of this treatment. Culp and Kaplan found it impossible to keep the podophyllum suspension confined to the lesions. I have modified their method by using a 10 per cent tincture of Resin of Podophyllum (U. S. P.). This is not an official preparation but is prepared for me by my pharmacist. This is applied to the surface of the lesions with a cotton swab or a camel's-hair brush. Usually only one
ANDERSON CR. TREATMENT OF CONDYLOMA ACUMINATUM WITH RESIN OF PODOPHYLLUM. Arch Derm Syphilol. 1946;54(1):66. doi:10.1001/archderm.1946.01510360070012
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