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December 1946

ANGIOMAS OF THE SCROTUM (ANGIOKERATOMA, FORDYCE): Compilation of Cases and Discussion of Nomenclature

Author Affiliations


From the Department of Dermatology and Syphilology, University of Southern California School of Medicine.

Arch Derm Syphilol. 1946;54(6):667-674. doi:10.1001/archderm.1946.01510410033003

SINCE Fordyce,1 in 1896, first described a case of "angiokeratoma of the scrotum," a state of confusion has existed in the classification and the nomenclature of this dermatosis. The confusion in nomenclature between angiokeratoma of the scrotum (Fordyce) and angiokeratoma (Mibelli2) was first recognized and discussed by Hudelo3 and later by Wile and Belote.4 Hudelo, in 1925, was the first investigator to stress the fact that a definite differentiation must be made between Mibelli's angiokeratoma, occurring on the extensor surfaces of the extremities associated with a history of pernio, and Fordyce's angiokeratoma or angiomas, occurring on the scrotum in subjects without a history of pernio. Wile and Belote,4 in 1928, stated that Fordyce's angiokeratoma was a disease entirely different from true angiokeratoma of Mibelli. These authors also discussed the similarity of the histologic pictures of senile angiomas and angiomas of the scrotum and

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