THE PARENTERAL use of penicillin has now reached the stage at which its efficacy in a wide variety of diseases has been well established, although its full clinical possibilities as a local therapeutic agent are yet to be realized.
Franks, Dobes and Romano1 have reported dramatic results in the treatment of 8 patients with impetigo contagiosa. Others who have reported good results in the treatment of impetigo are Kierland,2 Garrod,3 Roxburgh, Christie and Roxburgh4 and Templeton, Clifton and Seeberg.5 Florey and Florey6 found penicillin ointment of value in the treatment of mixed infections of chronic wound sinuses. Johnson7 has reported excellent results in the treatment of 25 patients with common pyodermas. Roxburgh, Christie and Roxburgh4 used a penicillin ointment to treat 15 patients with sycosis barbae, obtaining permanent cures in 5 and initial cures in 3, with relapse and permanent cure following
WRIGHT CS, GROSS ER. TOPICAL TREATMENT WITH PENICILLIN OINTMENT. Arch Derm Syphilol. 1947;55(1):52–56. doi:10.1001/archderm.1947.01520010056006
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