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Article
February 1947

EOSINOPHILIC GRANULOMA OF THE SKIN: Its Relation to Erythema Elevatum Diutinum and Eosinophilic Granuloma of the Bone; Report of a Case

Author Affiliations

BOSTON

From the Departments of Dermatology and Pathology, Massachusetts General Hospital.

Arch Derm Syphilol. 1947;55(2):194-211. doi:10.1001/archderm.1947.01520020043003
Abstract

THE CASE to be presented has many clinical and histologic features in common with erythema elevatum diutinum and with eosinophilic granuloma of the skin. Eosinophilic granuloma has been described as a disease of the skin and of the bone, but whether the two diseases are related is not yet certain.

In the following report the clinical and histologic appearance of erythema elevatum diutinum, eosinophilic granuloma of the skin and eosinophilic granuloma of the bone will be reviewed and the possibility of a relationship discussed.

REPORT OF A CASE  A 47 year old woman first noticed in 1935 a small purple patch in the left malar region. In 1939 two additional lesions appeared, one on the right cheek and one just below the first lesion on the left cheek. All three patches gradually increased in size, and by 1942 the two on the left cheek had united. The lesions were not

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