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Article
February 1947

GRANULOMATOUS HODGKIN'S DISEASE OF THE SKIN WITH EXTREME EOSINOPHILIA (Eosinophilic Granuloma of the Skin?)

Author Affiliations

ATLANTA, GA.; PHILADELPHIA

Arch Derm Syphilol. 1947;55(2):212-221. doi:10.1001/archderm.1947.01520020061004
Abstract

COMMONLY, Hodgkin's disease expresses itself on the skin in a nonspecific manner, such as by pruritus, urticaria and scaly erythrodermas. Relatively seldom do granulomatous lesions appear. In our case, five biopsies of specimens of the skin and two of specimens of the lymph nodes furnished an unusual opportunity for correlation of the reactions in these two tissues and for observation of the tissue processes from their beginning to maturity. Moreover, polymorphonuclear leukocytes were present in enormous numbers; the neutrophilic ones, which are so rare in this disease, bespoke an acute type of reaction, and the eosinophilic ones raised the question of whether eosinophilic granuloma of the skin was related.

REPORT OF A CASE  The patient was first seen at Grady Hospital on May 29, 1935, with a complaint of painful menstruation. The past history was essentially noncontributory and insignificant. The blood pressure was 160 systolic and 95 diastolic. The other

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