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February 1947


Arch Derm Syphilol. 1947;55(2):251-255. doi:10.1001/archderm.1947.01520020106008

DEPOSITS of amyloid in the skin associated with widespread systemic deposits have become more generally recognized recently. Primary amyloidosis of the skin must be exceedingly uncommon, however, the first report in the American literature appearing in 1931.1 This was based on European, not American, cases. For the condition to be considered primary, there should be no evidence of deposits of amyloid in the viscera. This can be ascertained after complete postmortem examination; hence any such diagnosis during life cannot be more than presumptive. The following case fulfils these requirements.

Previous reports of this case have appeared, once in 1939 before the Philadelphia Dermatological Society2 and prior to that by Herman and Lyon in 1921.3 The present report summarizes the findings which appeared in these reports and the subsequent course.

REPORT OF A CASE  J. R., a Spaniard residing in Cuba from 1889 to 1906, suffered a severe

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