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March 1947


Author Affiliations


From the Department of Dermatology and Syphilology and the Department of Pathology, the University of Oklahoma School of Medicine.

Arch Derm Syphilol. 1947;55(3):369-374. doi:10.1001/archderm.1947.01520030062009

THE CLINICAL history and the observations at necropsy of a 7 week old white girl afflicted with the rare disease epidermolysis bullosa hereditaria are presented. Herlitz1 in 1935 collected 14 such cases and added 8 of his own. He defined the disease as a familial or hereditary tendency to progressive blistering of the skin and mucous membranes apparent at birth or soon after. Herlitz further stated that this type of epidermolysis differs from the classic simple and dystrophic forms in that it always leads to early death, usually occurring before the third month. Additional cases reported since 1935 are those of Davidson,2 Brandberg,3 Schroder and Wells4 and Black, Wilhelm, Gilbert and White.5 The case herein recorded is the twenty-seventh.

REPORT OF A CASE  The patient, B. S. H., a 7 week old white girl, was admitted to the University Hospitals on Oct. 29, 1944, with