THE FIRST authentic case of the simultaneous occurrence of malignant disease and leukemia was described by Whipham in 1878. A total of 21 cases of combined leukemia and malignant growths had been reported up to 1944, according to Morrison, Feldman and Samwick.1 All the malignant growths involved internal organs except those in the cases of Fuhs,2 Scheuffler3 and Schreiner and Wehr,4 who described epitheliomas of the skin. While Schreiner and Wehr described a case of epithelioma of the ear, associated with chronic lymphatic leukemia, originating on a normal skin, the epitheliomas described by Fuhs and Scheuffler developed on a leukemid. Besides these reports, Schreiner and Wehr had, among 11,212 cases of malignant disease, an additional 4 cases. Since the association of leukemia with malignant growth, particularly the combination with cancer of the skin, is rare, we deemed it to be of sufficient interest to report the
REISS F, KONHEIM W. BASAL SQUAMOUS CELL EPITHELIOMA ASSOCIATED WITH LEUKEMIA. Arch Derm Syphilol. 1947;55(4):507–511. doi:10.1001/archderm.1947.01520040076007
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