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Article
May 1947

LEISHMANIA VACCINE TEST IN LEISHMANIASIS OF THE SKIN (ORIENTAL SORE): Quantitative Experiments

Author Affiliations

JERUSALEM, PALESTINE

From the Dermatological Department of the Rothschild-Hadassah University Hospital, Head, Dr. A. Dostrovsky.

Arch Derm Syphilol. 1947;55(5):658-663. doi:10.1001/archderm.1947.01520050060008
Abstract

THE POSITIVE result of an intracutaneous leishmania vaccine test indicates that a person is going or has gone through an infection of leishmaniasis cutis. No information can, however, be derived from the outcome of the test as to the special type of leishmaniasis, which in this part of the world shows great diversity in its aspect and development.

When tests are performed on a large material it has been noted that the same dose that in one infected person provokes a necrotic reaction is in another scarcely able to elicit a positive response at all. It was, therefore, interesting to study the law underlying this peculiar phenomenon.

While in connection with tuberculosis this question offers great difficulty, since a large proportion of all adults give a positive reaction anyway, my associates and I were in the case of leishmaniasis guided by the more or less characteristic scar which is invariably

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