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Article
May 1947

SYSTEMIC TREATMENT OF CREEPING ERUPTION

Author Affiliations

RALEIGH, N. C.

Formerly Commander in the Medical Corps of the United States Naval Reserve.

Arch Derm Syphilol. 1947;55(5):664-673. doi:10.1001/archderm.1947.01520050066009
Abstract

IN THE time-honored but, unfortunately, always awkward and frequently unsatisfactory treatment of larva migrans as encountered in this country, various physical and chemical local applications have been employed. Since the classic delineation of this condition as seen in the southeastern United States by Kirby-Smith, Dove and White1 in 1926, there had been no radical changes in its therapy until D. C. Smith2 introduced the use of fuadin in 1943. Following this real advance in therapeutics, reports have appeared which in the main substantiate the observation that this antimony compound is in many instances toxic for the larva (Wilson3 and Rubin4). However, some investigators have found that the medicament is frequently ineffective in completely eradicating the infestation (Blank5 and Dolce and Franklin6). Recently Hailey and Hailey7 reverted to local therapy after becoming discouraged with the use of fuadin systemically and reported cures with the

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