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Pemphigus Vulgaris. Presented by Dr. Lesser M. Fruchtbaum.
Mrs. V. N., aged 36, was seen at the dermatologic clinic of the Long Island College Hospital on Aug. 6, 1945, at which time she complained of a rash of nine months' duration. Prior to the appearance of the present eruption she had been taking medicaments for headaches and hay fever. She stated that since her present illness she has lost 15 pounds (6.8 Kg.).Examination reveals an emaciated woman, weighing 90 pounds (40.8 Kg.). The mouth, palate, buccal mucosa and tongue are covered with large bullae, varying from the size of a hazelnut to that of a walnut and filled with a red fluid. The upper and lower extremities, especially the hands and fingers, are covered with hemorrhagic bullae and exfoliative lesions. The trunk is covered with similar lesions, but to a less degree.The Nikolsky sign was positive. The Wassermann
Davidson DM, Silvers SM. BROOKLYN DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1947;55(5):720–723. doi:https://doi.org/10.1001/archderm.1947.01520050122020
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