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May 1947


Arch Derm Syphilol. 1947;55(5):728-739. doi:10.1001/archderm.1947.01520050130022

Epidermolysis Bullosa. Presented by Dr. Norman N. Epstein.  A. A B., a 7 1/2 year old Mexican boy, was first presented before the American Dermatological Association in June 1938 (Epidermolysis Bullosa, Arch. Dermat. & Syph.39:1052 [June] 1939). His general condition at birth was good, but physical examination one hour later revealed clubfeet and circumscribed, sharply defined, depressed, smooth, reddened areas on the ankles and feet. A bulla, 1 cm. in diameter, was present on the dorsum of the left index finger. Buccal lesions were also present.Gradual improvement occurred, but one year later more bullae spontaneously appeared at the pressure sites and on the abdomen, mouth and penis. The course up to the present has been one of recurrent formation of vesicles and bullae, involving at various times most of the extensor surfaces and the buccal mucosa. The lesions heal with some scarring and pigmentation.Treatment has emphasized

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