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Article
June 1947

EFFECTS OF GLYCERITE OF HYDROGEN PEROXIDE ON INFECTIONS OF THE SKIN AND MUCOUS MEMBRANES

Author Affiliations

Physician in Chief, Department of Dermatology, Boston Dispensary; Physician in Chief, Department of Allergy, Boston Dispensary BOSTON

Arch Derm Syphilol. 1947;55(6):801-809. doi:10.1001/archderm.1947.01520060063007
Abstract

ALTHOUGH previous studies have reported on the stability,1 the antibacterial action,2 the effects on tissue tolerance3 and the clinical results achieved with glycerite of hydrogen peroxide in infectious conditions such as otitis media, these have been submitted or have appeared so recently that the composition and properties of the solution require brief description.

An analysis of the field of topical antisepsis demonstrates the fact that hydrogen peroxide possesses virtues which entitle it to a higher position than that which it holds in the opinions of students of this subject. It is true that in the presence of peroxidase its aqueous solutions decompose so rapidly that bacteria are little affected and that in the absence of peroxidase its effects are so mild that it has been given a low phenol coefficient. On the other hand, when its rate of decomposition can be controlled so that the effects of

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