CHEILITIS is one of the most commonly seen dermatoses in clinical practice. Among the most frequent causes of this disease in women is the dye used to impart lasting qualities to indelible lipsticks. This dye is dibromfluorescein, tribromfluorescein or tetrabromfluorescein.
Many other causative agents of cheilitis have been reported in the literature. Various authors have reported cases of cheilitis due to the following: actinic or chemically active rays of sunlight,1 cold urticaria,2 carmine and anilin dyes in liquid rouge,3 trout,4 lipstick,5 methyl heptine carbonate in the perfume of lipstick,6 dental plates ("hecolite"),7 eosin dye in lipstick,8 denture creams containing oil of anise,9 lipstick in which local factors play a part,10 mouth washes and cigaret holders,11 derivatives of bromfluorescein (with photosensitization a factor to be considered), a husband's moustache wax, amalgam fillings for teeth, toothpaste and a preparation for gums
ZAKON SJ, GOLDBERG AL, KAHN JB. LIPSTICK CHEILITIS: A Common Dermatosis: Report of Thirty-Two Cases. Arch Derm Syphilol. 1947;56(4):499–505. doi:https://doi.org/10.1001/archderm.1947.01520100095013
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