ACNE rosacea belongs to that group of cutaneous diseases which have been attributed to many causes, as often is the case in a disease of obscure causation. The following have been advanced as causal factors: alcoholism, pelvic congestion, menopausal flushing, vasomotor disturbances of the male climacteric, gastrointestinal disorders (some claim 90 per cent of cases due to this factor), focal infection, obesity, organic disturbances, vasomotor neuroses, exposure to the elements and pastries and pies in the diet.
It is my belief that most, if not all, cases of rosacea are due to a vitamin B complex deficiency and that all the causes heretofore mentioned may be exciting or underlying factors, but are not immediately causal.
The term "brandy face," which both laymen and dermatologists often have used, we know today to be misleading. Although it is true that alcoholism is frequently a predisposing factor, I believe it to be so
TULIPAN L. ACNE ROSACEA: A Vitamin B Complex Deficiency. Arch Derm Syphilol. 1947;56(5):589–591. doi:10.1001/archderm.1947.01520110035005
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