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February 1948


Arch Derm Syphilol. 1948;57(2):235-239. doi:10.1001/archderm.1948.01520140097012

THE RARE disease, Vogt-Koyanagi syndrome, has not been previously described, to our knowledge, in the dermatologic literature. Inasmuch as the few reported cases have appeared only in the annals of ophthalmology, the present case is deemed worthy of presentation as an example of this syndrome, the chief manifestations of which are uveitis, canities, alopecia, vitiligo and dysacousia.


History.—  I. S., a white woman aged 42, was first observed on June 12, 1943, with an erythematous scaling eruption involving the eyelids and surrounding skin. Subsequent examinations and observations proved the eruption to be contact dermatitis, which subsided on the removal of the offending agent, i. e., nail polish. Within the course of one year, the eruption underwent several remissions and exacerbations, until the patient was finally convinced, to her own satisfaction, that she was unable to tolerate nail polish. At the end of this period, she complained

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