IN 1916 Sutton1 called attention to a leukopigmentary anomaly which he named leukoderma acquisitum centrifugum. Hyde2 is credited by Sutton in his textbook with first recognizing the disease when he presented a case before the Chicago Dermatologic Society in 1906 under the title "Vitiligo With a Central Mole." However, Hebra and Kaposi3 mentioned the phenomenon in their textbook as early as 1874. In a general discussion of vitiligo they spoke casually of vitiligo that formed around preexisting nevi, and they cited other authors as to the causal role of injury, pressure, burns and constitutional disease in depigmentations. In 1910 Rolleston4 noted and recorded the anomaly in a patient who was suffering from abdominal carcinomatosis. This patient was jaundiced, and the vitiliginous area surrounding the nevus was observed to take the yellow discoloration. In 1915 Almkvist5 described a case of this sort, but called the achromic
LEIDER M, COHEN TM. LEUKODERMA ACQUISITUM CENTRIFUGUM. Arch Derm Syphilol. 1948;57(3_PART_I):380–386. doi:10.1001/archderm.1948.01520150102013
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