The treatment of plantar warts has always been a difficult therapeutic problem. The almost invariable localization of such warts on the weight-bearing portions of the sole necessitates a form of treatment which will destroy the growth and at the same time permit active weight bearing on the treated area.
The number of methods of treatment advocated for this disease indicates that as yet there is no single completely satisfactory type of treatment. Surgical excision and curettage frequently prevent weight bearing for as long as three weeks. The possibility of a tender scar's resulting from such treatment must always be borne in mind. Trichloroacetic acid and other chemical mediums of destruction are slow, tedious and frequently followed by recurrence. Radiotherapy can be the method of choice only in the most experienced hands.
The report of Culp and Kaplan in 19441 on the treatment of condyloma acuminatum with podophyllum presented a
KURTIN A, YONTEF R. PODOPHYLLUM THERAPY FOR PLANTAR WARTS. Arch Derm Syphilol. 1948;57(3_PART_I):395–396. doi:10.1001/archderm.1948.01520150117016
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