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May 1948


Author Affiliations


From the Department of Dermatology, University of Pittsburgh.

Arch Derm Syphilol. 1948;57(5):822-827. doi:10.1001/archderm.1948.01520180039005

DURING the past several years we have studied a number of patients whose clinical and laboratory observations are grouped and presented herewith rather than details of individual cases. These patients were past middle life and presented varying degrees of edema, particularly of the aspect of the legs below the knees, usually associated with a chronic erythematous, papular, vesicular, pustular, exudative or squamous inflammatory process, of varying degrees of severity and involving the same areas. In some cases the eczematous process was much more extensive, and in a few instances chronic generalized erythroderma was present. In one of the latter, a mild diabetes was evidenced by reduced sugar tolerance. Hemostasis of varicosities or cardiac or renal disease was ruled out in all cases. Most of our patients had dental caries and/or unsatisfactory masticating surfaces. A feeling of weight and fulness with much gas after meals was frequently noted. Anorexia was usual.

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