THE LARGE shifts of population which accompanied the recent war created a hitherto unprecedented number of cases of granuloma in the North. Thus, in the space of three years, in the city of Chicago, where the disease was a relative rarity, almost 100 patients were seen and treated at the Chicago Intensive Treatment Center. It appears timely, in view of the large increase in the number of cases seen in northern cities recently, to review the literature on this disease, with particular attention to the newer methods of treatment.
McLeod1 in India first described the disease as a "serpiginous ulceration of the genitals," and Conyers and Daniels2 in 1896 first recognized the disease as a distinct clinical entity. In 1905 Donovan3 in India demonstrated the organism which today bears his name. In 1913 Aragao and Vianna4 introduced antimony potassium tartrate in the treatment of the disease.