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Article
July 1948

TREATMENT OF EARLY SYPHILIS WITH PENICILLIN IN OIL AND WAX

Author Affiliations

ATLANTA, GA.

From the Clinic for Genitoinfectious Diseases, Grady Hospital, Department of Medicine, Emory University School of Medicine, and the Georgia Department of Public Health.

Arch Derm Syphilol. 1948;58(1):34-40. doi:10.1001/archderm.1948.01520200037004
Abstract

THE with penicillin as an office procedure is highly desirable, since, for social or financial reasons, many patients wish to avoid hospitalization. The delayed absorption of penicillin in peanut oil and wax permits the use of this preparation on an ambulatory basis, and several reports have appeared in which this form of treatment has been shown to be satisfactory in the treatment of early syphilis.1

During the past year I have used penicillin in oil and wax alone in the treatment of 78 patients with primary and secondary syphilis. This report presents the results obtained and the untoward reactions that I observed in this group of patients.

MATERIAL AND PROCEDURE  From February 1946 to August, 78 patients with early syphilis were treated with penicillin in oil and wax. Three of these patients failed to return for follow-up observation and are not included in this report. Of the remaining 75

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