THE PURPOSE of this paper is to present additional cases of leukoderma produced by antioxidizing agents contained in manufactured articles. The chemistry of rubber and rubberized industries has developed not only along lines of greater production of synthetic products but also toward extending the aging of these goods. For this latter objective, the chemical compound "agarite alba," the trade name for monobenzyl ether of hydroquinone, an antioxidant of pigment, is usually added. This observation was first established by Oliver, Schwartz and Warren.1 These authors observed in the tanning industry occupational leukoderma in men wearing rubber gloves which contained this antioxidant to help the aging of rubber. Another observation was made of occupational leukoderma in a woman employed to wash contraceptive diaphragms in a gynecologic laboratory.2
REPORT OF CASES
E. B., a man aged 29, consulted me because of the appearance of white patches on the hands.
SPENCER GA. LEUKODERMA PRODUCED BY ANTIOXIDANTS: Report of Cases. Arch Derm Syphilol. 1948;58(2):215–219. doi:10.1001/archderm.1948.01520210125018
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