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October 1948

EOSINOPHILIC GRANULOMA: With Simultaneous Involvement of Skin and Bones

Author Affiliations


From the Section of Dermatology, University of Chicago (Chief of Service, Dr. Stephen Rothman).

Arch Derm Syphilol. 1948;58(4):372-380. doi:10.1001/archderm.1948.01520230017002

EOSINOPHILIC granuloma of the bone has been established as a disease entity by Otani and Ehrlich1 and by Lichtenstein and Jaffe,2 in 1940. The eosinophilic granulomas of the skin as reported in the literature have recently been reviewed by Weidman,3 Lewis and Cormia,4 Lever5 and Dobes and Weidman.6 The cutaneous manifestations of eosinophilic granuloma have varied so widely in their clinical and histopathologic features that the disease is not yet considered as a disease entity.

REPORT OF A CASE  V. M.,7 an 11 year old white girl, was first seen at the University of Chicago Clinics on Jan. 9, 1947. She complained of tender tumefactions and ulcerations of the skin on the upper part of the chest and scalp. She had been well until the age of 2 years, when she became ill with measles and mumps at the same time. During this

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