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November 1948


Arch Derm Syphilol. 1948;58(5):566-589. doi:10.1001/archderm.1948.01520240114005

Localized Scleroderma. Presented by Dr. Franklin I. Ball.  A. A., a girl aged 13, five years ago noticed the appearance of small discolored spots on both flanks; they have enlarged to their present size, and additional lesions have appeared on the back, close to the spinal column. The lesions are sharply outlined, ovoid plaques, ranging from the size of a half-dollar to that of a palm, which follow the lines of cleavage and are symmetrically distributed. There is a moderate degree of induration. The lesions are somewhat depressed, and some of the more recent ones have a faint violaceous areola.Hemograms and results of urinalyses were normal, and Wassermann reactions of the blood were negative. Microscopic examination showed thickening of the corium by dense, undulating, refractile connective tissue fibers. A slight lymphocytic infiltration was present immediately beneath the basal layer and about the adjacent vessels.

DISCUSSION  Dr. Andrew G. Lighter

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