IN PRELIMINARY clinical trial, tetra-chloro-para-benzoquinone in high concentration proved nontoxic when applied to the human skin as an ointment.1 Moreover, it was therapeutically active in the treatment of various forms of tinea capitis.1 For a number of years an impure preparation of this drug, spergon® (a mixture of chemically pure tetrachloroparabenzoquinone, 99 per cent, and disodium phosphate, 1 per cent, manufactured by the United States Rubber Company), has been successfully used as a protectant for the control of fungi that attack seeds.2 The present report deals with further experiences in the management of tinea capitis as well as several other human fungous infections.
MATERIALS AND METHODS
Cases were obtained from the dermatologic clinic of a general city hospital and from private practice. Fifty-one of the total of 155 patients were hospitalized, not because of the greater severity of their lesions, but in order to control them more